Treatment of Guillain-Barre Syndrome 01

Topic: Adult

Created on Friday, October 3 2008 by jdmiles

Last modified on Friday, October 3 2008.

 
        A) IVIG and corticosteroids are equally effective.
 
        B) Plasmapheresis is more effective than IVIG, and has fewer side effects
 
        C) Plasmapheresis is more effective than corticosteroids.
 
        D) Plasmapheresis and corticosteroids are equally effective.
 
        E) Plasmapheresis is more effective than IVIG, and there is no significant difference in side effects
 

 

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This question was created on October 03, 2008 by jdmiles.
This question was last modified on October 03, 2008.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS

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A) IVIG and corticosteroids are equally effective.

This answer is incorrect.

The patient has Guillain-Barre syndrome (GBS). In the treatment of GBS, IVIG and plasmapheresis are both more effective than corticosteroids. There is no clear difference in efficacy between IVIG and plasmapheresis, but IVIG has fewer side effects.  (See References)

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B) Plasmapheresis is more effective than IVIG, and has fewer side effects

This answer is incorrect.

The patient has Guillain-Barre syndrome (GBS). In the treatment of GBS, IVIG and plasmapheresis are both more effective than corticosteroids. There is no clear difference in efficacy between IVIG and plasmapheresis, but IVIG has fewer side effects.  (See References)

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C) Plasmapheresis is more effective than corticosteroids.

This answer is correct.

The patient has Guillain-Barre syndrome (GBS). In the treatment of GBS, IVIG and plasmapheresis are both more effective than corticosteroids. There is no clear difference in efficacy between IVIG and plasmapheresis, but IVIG has fewer side effects.  (See References)

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D) Plasmapheresis and corticosteroids are equally effective.

This answer is incorrect.

The patient has Guillain-Barre syndrome (GBS). In the treatment of GBS, IVIG and plasmapheresis are both more effective than corticosteroids. There is no clear difference in efficacy between IVIG and plasmapheresis, but IVIG has fewer side effects.  (See References)

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E) Plasmapheresis is more effective than IVIG, and there is no significant difference in side effects

This answer is incorrect.

The patient has Guillain-Barre syndrome (GBS). In the treatment of GBS, IVIG and plasmapheresis are both more effective than corticosteroids. There is no clear difference in efficacy between IVIG and plasmapheresis, but IVIG has fewer side effects.  (See References)

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References:

1. Winer, J.B. (2002). "Treatment of Guillain-Barré syndrome." QJM, 95(11) 717-21. (PMID:12391383)

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adult
Treatment of Guillain-Barre Syndrome 01
Question ID: 100308124
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 10/03/2008
Modified: 10/03/2008
Estimated Permutations: 75600