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Muscle Fiber Histology 02

Topic: Pathology

Created on Thursday, December 20 2007 by jdmiles

Last modified on Thursday, December 20 2007.

This photomicrograph shows a cytochrome C oxidase stain of skeletal muscle. In normal muscle, which of the following statements is true about the fibers that stain DARKER with cytochrome C oxidase?

 
        A) They are type 1 fibers
 
        B) They have a more anaerobic metabolism compared to the lighter fibers
 
        C) There is no functional difference between cells that stain differently
 
        D) They are type 2 fibers
 
        E) They contract more rapidly than the lighter fibers
 

 


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This question was created on December 20, 2007 by jdmiles.
This question was last modified on December 20, 2007.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) They are type 1 fibers

This answer is correct.


Cytochrome C oxidase is a marker of mitochondrial activity. In normal muscle, type 1 fibers stain darker than type 2 fibers with this type of stain.
Type 1 fibers tend to contract more slowly. They are more fatigue resistant, and have a more oxidative metabolism than type 2 fibers.
Type 2 fibers are faster, more easily fatigued, and their metabolism tends to be more anaerobic (glycolytic) compared to type 1 fibers.  (See References)

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B) They have a more anaerobic metabolism compared to the lighter fibers

This answer is incorrect.


Cytochrome C oxidase is a marker of mitochondrial activity. In normal muscle, type 1 fibers stain darker than type 2 fibers with this type of stain.
Type 1 fibers tend to contract more slowly. They are more fatigue resistant, and have a more oxidative metabolism than type 2 fibers.
Type 2 fibers are faster, more easily fatigued, and their metabolism tends to be more anaerobic (glycolytic) compared to type 1 fibers.  (See References)

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C) There is no functional difference between cells that stain differently

This answer is incorrect.


Cytochrome C oxidase is a marker of mitochondrial activity. In normal muscle, type 1 fibers stain darker than type 2 fibers with this type of stain.
Type 1 fibers tend to contract more slowly. They are more fatigue resistant, and have a more oxidative metabolism than type 2 fibers.
Type 2 fibers are faster, more easily fatigued, and their metabolism tends to be more anaerobic (glycolytic) compared to type 1 fibers.  (See References)

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D) They are type 2 fibers

This answer is incorrect.


Cytochrome C oxidase is a marker of mitochondrial activity. In normal muscle, type 1 fibers stain darker than type 2 fibers with this type of stain.
Type 1 fibers tend to contract more slowly. They are more fatigue resistant, and have a more oxidative metabolism than type 2 fibers.
Type 2 fibers are faster, more easily fatigued, and their metabolism tends to be more anaerobic (glycolytic) compared to type 1 fibers.  (See References)

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E) They contract more rapidly than the lighter fibers

This answer is incorrect.


Cytochrome C oxidase is a marker of mitochondrial activity. In normal muscle, type 1 fibers stain darker than type 2 fibers with this type of stain.
Type 1 fibers tend to contract more slowly. They are more fatigue resistant, and have a more oxidative metabolism than type 2 fibers.
Type 2 fibers are faster, more easily fatigued, and their metabolism tends to be more anaerobic (glycolytic) compared to type 1 fibers.  (See References)

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References:

1. Prayson, R.A., and Goldblum, J.R. (Eds.) (2005). Neuropathology. Elsevier Churchill Livingstone, Philadelphia. (ISBN:0443066582) Advertising:
2. Kandel, E.R., Schwartz, J.H., and Jessel, T.M. (2000). Principles of Neural Science, 4th ed. McGraw-Hill, New York. (ISBN:0838577016)Advertising:
3. / Alan Stevens, James Lowe. . London : Gower , 1992 (ISBN:0397446330)
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pathology
Muscle Fiber Histology 02
Question ID: 122007037
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 12/20/2007
Modified: 12/20/2007
Estimated Permutations: 360

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