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Neuromuscular Disorders 01

Topic: Pathology

Created on Sunday, December 23 2007 by jdmiles

Last modified on Sunday, December 23 2007.

The Gomori trichrome stained muscle biopsy shown above is most consistent with which of the following disorders?

 
        A) Duchenne muscular dystrophy
 
        B) Becker muscular dystrophy
 
        C) Nemaline myopathy
 
        D) Inclusion body myositis
 
        E) Central core disease
 

 


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This question was created on December 23, 2007 by jdmiles.
This question was last modified on December 23, 2007.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) Duchenne muscular dystrophy

This answer is incorrect.


The pathology shown is most consistent with nemaline myopathy. The nemaline rods are the dark inclusions at the periphery of the muscle fibers.  (See References)

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B) Becker muscular dystrophy

This answer is incorrect.


The pathology shown is most consistent with nemaline myopathy. The nemaline rods are the dark inclusions at the periphery of the muscle fibers.  (See References)

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C) Nemaline myopathy

This answer is correct.


The pathology shown is most consistent with nemaline myopathy. The nemaline rods are the dark inclusions at the periphery of the muscle fibers.  (See References)

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D) Inclusion body myositis

This answer is incorrect.


The pathology shown is most consistent with nemaline myopathy. The nemaline rods are the dark inclusions at the periphery of the muscle fibers.  (See References)

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E) Central core disease

This answer is incorrect.


The pathology shown is most consistent with nemaline myopathy. The nemaline rods are the dark inclusions at the periphery of the muscle fibers.  (See References)

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References:

1. Prayson, R.A., and Goldblum, J.R. (Eds.) (2005). Neuropathology. Elsevier Churchill Livingstone, Philadelphia. (ISBN:0443066582)Advertising:
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pathology
Neuromuscular Disorders 01
Question ID: 122307204
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 12/23/2007
Modified: 12/23/2007
Estimated Permutations: 600

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