Adverse effects of AEDs 13

Topic: Pharmacology

Created on Saturday, December 8 2007 by jdmiles

Last modified on Saturday, December 8 2007.

 
        A) Hepatotoxicity
 
        B) Hyperactivity
 
        C) Aplastic anemia
 
        D) Renal calculi
 
        E) Irritability
 

 

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This question was created on December 08, 2007 by jdmiles.
This question was last modified on December 08, 2007.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS

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A) hepatotoxicity

This answer is incorrect.

Hepatotoxicity is a hallmark side effect of valproate, but is less characteristic of zonisamide.  (See References)

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B) hyperactivity

This answer is incorrect.

Hyperactivity is a hallmark side effect of vigabatrin, but is less characteristic of zonisamide.  (See References)

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C) aplastic anemia

This answer is incorrect.

Aplastic anemia is a hallmark side effect of felbamate, but is less characteristic of zonisamide.  (See References)

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D) renal calculi

This answer is correct.

Side effects of zonisamide include renal calculi.  (See References)

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E) irritability

This answer is incorrect.

Irritability is a hallmark side effect of vigabatrin, but is less characteristic of zonisamide.  (See References)

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References:

1. Greenwood, R.S. (2000). "Adverse effects of antiepileptic drugs." Epilepsia, 41 Suppl 2 S42-52. (PMID:10885739)

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pharmacology
Adverse effects of AEDs 13
Question ID: 12080713
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 12/08/2007
Modified: 12/08/2007
Estimated Permutations: 4315200