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Cerebral blood flow 01

Topic: Pharmacology

Created on Friday, September 15 2006 by

Last modified on Friday, September 15 2006.

A 75 year-old sunflower seller presents is admitted to the neurosciences ICU after head trauma. Among other interventions, an arterial line and an intraventricular catheter are placed.


If his mean arterial pressure is 125 mmHg and his intracranial pressure is 75 mmHg, what is his cerebral perfusion pressure?

 
        A) 15 mmHg
 
        B) 50 mmHg
 
        C) 60 mmHg
 
        D) 5 mmHg
 
        E) 25 mmHg
 

 


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ANSWERS AND EXPLANATIONS




A) 15 mmHg

This answer is incorrect.


CPP = MAP - ICP.

Refer to the correct answer for further explanation.  (See References)

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B) 50 mmHg

This answer is correct.


Cerebral perfusion pressure (CPP) is the net pressure of the blood flowing through the brain. It is one of the determinants of cerebral blood flow. CPP must be regulated within narrow limits. If it drops too low, ischemia will result. CPP is defined by the following equation:
CPP = MAP - ICP,

where MAP is mean arterial pressure, and ICP is Intracranial pressure.
In this unfortunate person's case, MAP = 125mmHg, and ICP =75 mmHg. Solving for CPP, 125 - 75 = 50 mmHg.  (See References)

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C) 60 mmHg

This answer is incorrect.


CPP = MAP - ICP.

Refer to the correct answer for further explanation.  (See References)

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D) 5 mmHg

This answer is incorrect.


CPP = MAP - ICP.

Refer to the correct answer for further explanation.  (See References)

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E) 25 mmHg

This answer is incorrect.


CPP = MAP - ICP.

Refer to the correct answer for further explanation.  (See References)

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References:

1. Suarez, J.I. (2004). Critical Care Neurology and Neurosurgery. Humana Press, Totowa, New Jersey.
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pharmacology
Cerebral blood flow 01
Question ID: 69151
Question written by . (C) FrontalCortex.com 2006-2009, all rights reserved. Created: 09/15/2006
Modified: 09/15/2006
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