Neurocutaneous Syndromes 02

Topic: Adult

Created on Saturday, February 17 2007 by jdmiles

Last modified on Saturday, February 17 2007.

 
        A) Lisch nodules
 
        B) Facial angiofibromas
 
        C) Paucity or absence of cutaneous lesions
 
        D) Moyamoya syndrome
 
        E) Cafe au lait spots
 

 

	= Go back to the top of the page.
	= Reload a different version of this question ().
	= Load a random question from the database.
	= Use this question as a template to create a totally NEW question.
	= Enter detailed rating for this question!
	= How users like you have rated this question.

This question was created on February 17, 2007 by jdmiles.
This question was last modified on February 17, 2007.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS

---

A) Lisch nodules

This answer is incorrect.

Lisch nodules are small, whitish spots (hamartomas) in the iris of the eye. They are pathognomonic for neurofibromatosis type 1 (NF1), and are not seen in NF2.  (See References)

Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 

---

B) facial angiofibromas

This answer is incorrect.

Facial angiofibromas are not characteristic of NF2. They are associated with tuberous sclerosis.  (See References)

Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 

---

C) paucity or absence of cutaneous lesions

This answer is correct.

Skin changes, including cafe au lait spots, molluscum fobrosum (cutaneous tumors), and freckling in the axillae and groin, are typical of neurofibromatosis type 1 (NF1), but are not characteristic of NF2.  (See References)

Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 

---

D) moyamoya syndrome

This answer is incorrect.

Moyamoya syndrome is a known complication of neurofibromatosis type 1 (NF1), but not of NF2.  (See References)

Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 

---

E) cafe au lait spots

This answer is incorrect.

Skin changes, including cafe au lait spots, molluscum fobrosum (cutaneous tumors), and freckling in the axillae and groin, are typical of neurofibromatosis type 1 (NF1), but are not characteristic of NF2.  (See References)

Please log in if you want to rate questions.

 

 

 

 

References:

1. Neurofibromatosis Fact Sheet, NINDS. NIH Publication No. 06-2126
2. Victor, M., and Ropper, A.H. (2001). Adams and Victor's Principles of Neurology, 7th Edition. McGraw-Hill, New York. Pp. 1069-1076.
3. Santos, C.C., Miller, V.S., and Roach, E.S. (2004). Neurocutaneous syndromes. In Bradley, W.G., Daroff, R.B., Fenichel, G.M., and Jankovic, J. (Eds.). Neurology in Clinical Practice, 4th Edition. Butterworth Heinemann, Philadelphia. Pp. 1867-1900.

Please log in if you want to rate questions.

 

FrontalCortex.com -- Neurology Review Questions -- Neurology Boards -- Board Review -- Residency Inservice Training Exam -- RITE Exam Review
adult
Neurocutaneous Syndromes 02
Question ID: 021707088
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 02/17/2007
Modified: 02/17/2007
Estimated Permutations: 491400