Type I Muscle Fibers

Topic: Physiology

Created on Sunday, November 9 2008 by jdmiles

Last modified on Sunday, November 9 2008.

 
        A) They are the darker-stained fibers on a basic ATPase stain of skeletal muscle
 
        B) They are the lighter-stained fibers on an acidic ATPase stain of skeletal muscle
 
        C) They contain fewer mitochondria than type II fibers
 
        D) They are the primary muscle fibers affected in congenital fiber-type disproportion myopathy
 
        E) They are the primary muscle fibers affected in disuse atrophy
 

 

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This question was created on November 09, 2008 by jdmiles.
This question was last modified on November 09, 2008.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS

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A) they are the darker-stained fibers on a basic ATPase stain of skeletal muscle

This answer is incorrect.

Type I muscle fibers are the lighter-stained fibers on a pH 9.4 (basic) ATPase stain of skeletal muscle. Although in the basic stain, type I fibers may still appear fairly dark, type II fibers appear even darker in this staining technique.
Reload this question to learn more stuff about muscle fiber types.  (See References)

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B) they are the lighter-stained fibers on an acidic ATPase stain of skeletal muscle

This answer is incorrect.

Type I muscle fibers are the darker-stained fibers on a pH 4.2 (acidic) ATPase stain of skeletal muscle. Type II fibers appear lighter in this staining technique.
Reload this question to learn more stuff about muscle fiber types.  (See References)

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C) they contain fewer mitochondria than type II fibers

This answer is incorrect.

Type I fibers contain more mitochondria than type II fibers.
Reload this question to learn more stuff about muscle fiber types.  (See References)

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D) they are the primary muscle fibers affected in congenital fiber-type disproportion myopathy

This answer is correct.

In congenital fiber-type disproportion myopathy, there is selective atrophy of type I muscle fibers.
Reload this question to learn more stuff about muscle fiber types.  (See References)

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E) they are the primary muscle fibers affected in disuse atrophy

This answer is incorrect.

In disuse atrophy, there is selective atrophy of type II muscle fibers.
Reload this question to learn more stuff about muscle fiber types.  (See References)

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References:

1. Preston, D.C., and Shapiro, B.E. (2005). Electromyography and Neuromuscular Disorders: Clinical-Electrophysiologic Correlations, 2nd Edition. Elsevier, Philadelphia. (ISBN:075067492X)	Advertising:
2. Nizar Souayah, Sami Khella. Neurology: McGraw-Hill specialty board review: examination & board review. New York : McGraw-Hill, Medical Pub. Division, c2005. (ISBN:0071378391)	Advertising:
3. Prayson, R.A., and Goldblum, J.R. (Eds.) (2005). Neuropathology. Elsevier Churchill Livingstone, Philadelphia. (ISBN:0443066582)	Advertising:

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physiology
Type I Muscle Fibers
Question ID: 110908126
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 11/09/2008
Modified: 11/09/2008
Estimated Permutations: 5140800